MYCN anticorps (full length)

N° du produit ABIN7878702

L’anticorps anti-MYCN Monoclonal Souris est utilisé pour la détection de MYCN dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IF.

Aperçu rapide pour MYCN anticorps (full length) (ABIN7878702)

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYCN est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: NMYC-1

Détail du produit anti-MYCN anticorps

Épitope: full length

Fonction: n-Myc Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant full-length human n-Myc protein was used as the immunogen for the n-Myc antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the n-Myc antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the n-Myc antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MYCN

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Autre désignation: n-Myc

Sujet: The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

UniProt: P04198