NEUROD2 anticorps (full length)
Aperçu rapide pour NEUROD2 anticorps (full length) (ABIN7878707)
Antigène
Voir toutes NEUROD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- NEUROD2 Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human NEUROD2 protein was used as the immunogen for the NEUROD2 antibody.
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal dilution of the NEUROD2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the NEUROD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))
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Autre désignation
- NEUROD2
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Sujet
- Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
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UniProt
- Q15784
Antigène
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