NME1 anticorps (full length)

N° du produit ABIN7878717

L’anticorps anti-NME1 Monoclonal Souris est utilisé pour la détection de NME1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour NME1 anticorps (full length) (ABIN7878717)

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NME1 est non-conjugé

Application: Western Blotting (WB)

Clone: CPTC-NME1-2

Détail du produit anti-NME1 anticorps

Épitope: full length

Fonction: NME1 Antibody / NM23

Purification: Protein G affinity chromatography

Immunogène: A recombinant full-length human NME1 protein was used as the immunogen for this NME1 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the NME1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the NME1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur NME1

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Autre désignation: NME1

Sujet: The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor.

UniProt: P15531

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process