Recombinant Nucleolin anticorps (full length)
Aperçu rapide pour Recombinant Nucleolin anticorps (full length) (ABIN7878734)
Antigène
Voir toutes Nucleolin (NCL) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Nucleolin Antibody (azide and preservative free)
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Purification
- Protein A affinity chromatography
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Immunogène
- Recombinant full length human protein was used as the immunogen for the Nucleolin antibody.
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Isotype
- IgG, kappa
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Indications d'application
- Optimal dilution of the Nucleolin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the Nucleolin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Nucleolin (NCL)
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Autre désignation
- Nucleolin
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Sujet
- Recognizes a protein of ~76 kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells.
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UniProt
- P19338
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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