NME2 anticorps (full length)
Aperçu rapide pour NME2 anticorps (full length) (ABIN7878746)
Antigène
Voir toutes NME2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- NDPK-B Antibody / Nucleoside diphosphate kinase B / NME2 (azide and preservative free)
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Purification
- Protein G affinity
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Immunogène
- A recombinant full-length human Nucleoside diphosphate kinase B protein was used as the immunogen for the NDPK-B antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the NDPK-B antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the NDPK-B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NME2 (Nucleoside diphosphate kinase B (NME2))
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Autre désignation
- NDPK-B
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Sujet
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
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UniProt
- P22392
Antigène
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