Recombinant PMEPA1 anticorps (full length)
Aperçu rapide pour Recombinant PMEPA1 anticorps (full length) (ABIN7878871)
Antigène
Voir toutes PMEPA1 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- full length
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Fonction
- Recombinant TMEPAI Antibody / PMEPA1
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant TMEPAI antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the recombinant TMEPAI antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the recombinant TMEPAI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
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Autre désignation
- TMEPAI
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Sujet
- PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Antigène
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