Cet anticorps anti-SIRT3 Monoclonal Souris (Clone PCRP-SIRT3-1C10) (ABIN7879051) détecte spécifiquement SIRT3 dans WB, ELISA, IF et FACS.
L’anticorps est réactif avec des échantillons de Humain.
SIRT3
Reactivité: Humain, Souris, Rat
WB, IHC, ELISA, ICC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the SIRT3 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
-20 °C
Stockage commentaire
Aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
SIRT3
(Sirtuin 3 (SIRT3))
Autre désignation
SIRT3
Sujet
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).