TAL1 anticorps (full length)

N° du produit ABIN7879114

Cet anticorps anti-TAL1 Monoclonal Souris (Clone TAL1-2707) (ABIN7879114) détecte spécifiquement TAL1 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TAL1 anticorps (full length) (ABIN7879114)

Antigène: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TAL1 est non-conjugé

Application: ELISA

Clone: TAL1-2707

Détail du produit anti-TAL1 anticorps

Épitope: full length

Fonction: TAL1 Antibody / T-cell acute lymphocytic leukemia protein 1

Purification: Protein G affinity chromatography

Immunogène: A recombinant human full-length TAL1 protein was used as the immunogen for the TAL1 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the TAL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TAL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur TAL1

Antigène: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Autre désignation: TAL1

Sujet: Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.

UniProt: P17542

Pathways: Stem Cell Maintenance