TMPRSS2 anticorps (full length)

N° du produit ABIN7879197

L’anticorps anti-TMPRSS2 Monoclonal Souris est utilisé pour la détection de TMPRSS2 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour TMPRSS2 anticorps (full length) (ABIN7879197)

Antigène: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TMPRSS2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: TMPRSS2-7420

Détail du produit anti-TMPRSS2 anticorps

Épitope: full length

Fonction: Transmembrane protease serine 2 Antibody / TMPRSS2 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the Transmembrane protease serine 2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Transmembrane protease serine 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Transmembrane protease serine 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur TMPRSS2

Antigène: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Autre désignation: Transmembrane protease serine 2

Sujet: Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland. TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain. TMPRSS2 is expressed as a full length form and a cleaved protease domain and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis.

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interactome