TTR anticorps (full length)
Aperçu rapide pour TTR anticorps (full length) (ABIN7879206)
Antigène
Voir toutes TTR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- full length
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Fonction
- Transthyretin Antibody / TTR / Prealbumin
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Purification
- Protein G affinity chromatography
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Immunogène
- Recombinant human full-length protein was used as the immunogen for the Transthyretin antibody.
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Isotype
- IgG2c, kappa
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Indications d'application
- Optimal dilution of the Transthyretin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the Transthyretin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TTR (Transthyretin (TTR))
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Autre désignation
- Transthyretin
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Sujet
- Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).
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UniProt
- P02766
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Pathways
- Hormone Transport
Antigène
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