UBE2B anticorps (full length)

N° du produit ABIN7879291

Cet anticorps anti-UBE2B Monoclonal Souris (Clone PCRP-UBE2B-1C7) (ABIN7879291) détecte spécifiquement UBE2B dans IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour UBE2B anticorps (full length) (ABIN7879291)

Antigène: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp UBE2B est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-UBE2B-1C7

Détail du produit anti-UBE2B anticorps

Épitope: full length

Fonction: UBE2B Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human UBE2B protein was used as the immunogen for the UBE2B antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the UBE2B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the UBE2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur UBE2B

Antigène: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Autre désignation: UBE2B

Sujet: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (ubiquitin-conjugating enzyme E2 A) and UBE2B (ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to post replication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.

UniProt: P63146