UBE2B anticorps (full length)

N° du produit ABIN7879292

Cet anticorps Souris Monoclonal détecte spécifiquement UBE2B dans IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour UBE2B anticorps (full length) (ABIN7879292)

Antigène: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp UBE2B est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-UBE2B-1C7

Détail du produit anti-UBE2B anticorps

Épitope: full length

Fonction: UBE2B Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human UBE2B protein was used as the immunogen for the UBE2B antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the UBE2B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the UBE2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur UBE2B

Antigène: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Autre désignation: UBE2B

Sujet: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (ubiquitin-conjugating enzyme E2 A) and UBE2B (ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to post replication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.

UniProt: P63146