L’anticorps anti-ZNF276 Monoclonal Souris est utilisé pour la détection de ZNF276 dans des échantillons de Humain. Il a été validé pour ELISA, IF et FACS.
ZNF276
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
FITC
Indications d'application
Optimal dilution of the ZNF276 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
-20 °C
Stockage commentaire
Aliquot the ZNF276 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
ZNF276
(Zinc Finger Protein 276 (ZNF276))
Autre désignation
ZNF276
Sujet
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.