ZNF276 anticorps (full length)
Aperçu rapide pour ZNF276 anticorps (full length) (ABIN7879348)
Antigène
Voir toutes ZNF276 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- full length
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Fonction
- ZNF276 Antibody
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human ZNF276 protein was used as the immunogen for the ZNF276 antibody.
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Isotype
- IgG2b
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Indications d'application
- Optimal dilution of the ZNF276 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the ZNF276 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ZNF276 (Zinc Finger Protein 276 (ZNF276))
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Autre désignation
- ZNF276
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Sujet
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.
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UniProt
- Q8N554
Antigène
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