ZNF408 anticorps (full length)

N° du produit ABIN7879354

Cet anticorps anti-ZNF408 Monoclonal Souris (Clone PCRP-ZNF408-1E5) (ABIN7879354) détecte spécifiquement ZNF408 dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ZNF408 anticorps (full length) (ABIN7879354)

Antigène: ZNF408 (Zinc Finger Protein 408 (ZNF408))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZNF408 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: PCRP-ZNF408-1E5

Détail du produit anti-ZNF408 anticorps

Épitope: full length

Fonction: ZNF408 Antibody / PRDM17

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human ZNF408 protein was used as the immunogen for the ZNF408 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the ZNF408 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ZNF408 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ZNF408

Antigène: ZNF408 (Zinc Finger Protein 408 (ZNF408))

Autre désignation: ZNF408

Sujet: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

UniProt: Q9H9D4