Recombinant Annexin VII anticorps

N° du produit ABIN7879981

Cet anticorps anti-Annexin VII Monoclonal Lapin (Clone 30A75) (ABIN7879981) détecte spécifiquement Annexin VII dans WB, IHC et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant Annexin VII anticorps (ABIN7879981)

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Annexin VII est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 30A75

Détail du produit anti-Annexin VII anticorps

Fonction: Annexin A7 Antibody / ANXA7

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Annexin A7 was used as the immunogen for the Annexin A7 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Annexin A7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Annexin A7 antibody at -20oC.

Détails sur Annexin VII

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Autre désignation: Annexin A7

Sujet: Annexin A7 antibody detects annexin A7, a calcium and phospholipid binding protein encoded by the ANXA7 gene. Annexin A7 belongs to the annexin protein family, which share conserved annexin repeat domains that mediate calcium dependent membrane interactions. This protein participates in exocytosis, membrane fusion, and calcium signaling, making it a key regulator of vesicular transport and cellular communication across multiple tissues.

Annexin A7 antibody is widely applied in neuroscience, cardiovascular biology, and oncology. In the nervous system, annexin A7 contributes to synaptic vesicle release and neurotransmitter secretion. In cardiac muscle, it supports calcium handling and myocardial contractility. Dysregulation of annexin A7 has been associated with several cancers, where it influences tumor growth, cell motility, and drug resistance. By detecting annexin A7, researchers can study its role in both normal physiology and disease mechanisms.

In western blot assays, annexin A7 antibody identifies protein bands of the expected molecular weight in tissue lysates. Immunohistochemistry maps annexin A7 expression in brain, heart, and epithelial tissues, while immunofluorescence highlights cytoplasmic and membrane localization. These applications enable detailed analysis of annexin A7 in cellular signaling and trafficking.

Annexin A7 is involved in calcium dependent regulation of phospholipase activity and contributes to processes including apoptosis, proliferation, and membrane repair. Altered expression has been linked to cancer biology, cardiovascular disorders, and neurological diseases. In oncology, annexin A7 has been studied as both a tumor suppressor and promoter, depending on cellular context. By applying annexin A7 antibody, scientists can investigate how annexin mediated pathways affect tumor progression and therapy response.

Beyond cancer and cardiovascular research, annexin A7 also plays roles in endocrine function, fertility, and immune signaling. Its presence in secretory cells suggests contributions to hormone release and immune mediator secretion. These diverse functions emphasize the importance of annexin A7 as a research target across multiple biological systems.

Annexin A7 antibody from NSJ Bioreagents delivers reliable specificity for detecting this multifunctional calcium binding protein. Its strong performance across techniques ensures accurate results, supporting basic research as well as translational studies in neuroscience, cardiology, and oncology.

UniProt: P20073