ABCB1 anticorps

N° du produit ABIN7880019

L’anticorps anti-ABCB1 Polyclonal Lapin est utilisé pour la détection de ABCB1 dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour ABCB1 anticorps (ABIN7880019)

Antigène: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-ABCB1 anticorps

Fonction: ABCB1 Antibody / P Glycoprotein / MDR1

Séquence: TKEALDESIP PVSFWRIMK

Purification: Antigen affinity purified

Immunogène: Amino acids TKEALDESIPPVSFWRIMK from the human protein were used as the immunogen for the ABCB1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ABCB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ABCB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ABCB1

Antigène: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Autre désignation: ABCB1

Sujet: P-GP, also called ABCB1, MDR1 and PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the bloodi 1/2brain barrier.

UniProt: P08183