Recombinant CD147 anticorps

N° du produit ABIN7880053

Cet anticorps anti-CD147 Monoclonal Lapin (Clone 30B80) (ABIN7880053) détecte spécifiquement CD147 dans WB, IHC, IF, IP et ICC. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Recombinant CD147 anticorps (ABIN7880053)

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD147 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: 30B80

Détail du produit anti-CD147 anticorps

Fonction: Bsg Antibody / CD147

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human CD147 was used as the immunogen for the Bsg antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Bsg antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Bsg antibody at -20oC.

Détails sur CD147

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Autre désignation: Bsg

Sujet: BSG antibody detects basigin, also known as CD147, an immunoglobulin superfamily member encoded by the BSG gene. Basigin is a transmembrane glycoprotein expressed in many tissues and cell types. It functions as a receptor and regulator of matrix metalloproteinases, monocarboxylate transporters, and extracellular signaling molecules. By modulating these pathways, basigin influences immune responses, metabolism, and tumor progression.

BSG antibody is widely used in immunology, oncology, and infectious disease research. In cancer, basigin promotes tumor invasion and metastasis by inducing matrix metalloproteinase activity. It also regulates metabolic processes by facilitating lactate transport through interactions with monocarboxylate transporters. By detecting basigin, researchers can study how CD147 contributes to the tumor microenvironment and cellular metabolism.

The antibody is suitable for western blotting, flow cytometry, immunohistochemistry, and immunofluorescence. In western blot assays, BSG antibody detects protein bands corresponding to basigin in multiple tissues. Flow cytometry enables quantitative assessment of CD147 expression on immune and tumor cells. Immunohistochemistry reveals tissue specific patterns, while immunofluorescence highlights subcellular localization at plasma membranes.

Basigin also plays roles in immunity and infectious disease. It regulates leukocyte activation, T cell function, and pathogen interactions. Basigin has been identified as a receptor for certain parasites and viruses, linking it to infectious disease research. By using BSG antibody, scientists can evaluate the role of CD147 in host pathogen interactions and immune regulation.

BSG antibody from NSJ Bioreagents provides strong specificity for detecting basigin in cancer, immunity, and metabolism. Its proven reliability across techniques ensures accurate results for both basic and translational studies.

UniProt: P18572

Pathways: S100 Proteins