Cadherin 5 anticorps

N° du produit ABIN7880132

Cet anticorps Chèvre Polyclonal détecte spécifiquement Cadherin 5 dans ELISA, FACS et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cadherin 5 anticorps (ABIN7880132)

Antigène: Cadherin 5 (CDH5)

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 5 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-Cadherin 5 anticorps

Fonction: Cadherin 5 Antibody / VE Cadherin

Séquence: KQARAHGKSV PE

Purification: Antigen affinity

Immunogène: Amino acids KQARAHGKSVPE were used as the immunogen for this Cadherin 5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Cadherin 5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X TBS, pH 7.3, with 0.5 % BSA (US sourced) and 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store the Cadherin 5 antibody at -20oC.

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: Cadherin 5

Sujet: Cadherin 5 is primarily expressed in endothelial cells, where it plays a critical role in regulating cell-cell adhesion and maintaining the integrity of the vascular barrier. Through its interactions with other Cadherin molecules and cytoskeletal components, Cadherin 5 helps to form adherens junctions, specialized structures that hold adjacent cells together and facilitate cell communication. Research has shown that mutations or dysregulation of Cadherin 5 can lead to various pathologies, including vascular dysfunction, increased permeability of blood vessels, and impaired wound healing. In addition, Cadherin 5 has been implicated in the progression of cancer, as aberrant expression of this molecule can promote tumor invasion and metastasis.

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2