Cathepsin D anticorps

N° du produit ABIN7880202

L’anticorps anti-Cathepsin D Monoclonal Souris est utilisé pour la détection de Cathepsin D dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Cathepsin D anticorps (ABIN7880202)

Antigène: Cathepsin D (CTSD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CTSD-4497

Détail du produit anti-Cathepsin D anticorps

Fonction: CTSD Antibody / Cathepsin D (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Purified His-tagged CTSD protein was used as the immunogen for the CTSD antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CTSD antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the CTSD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: CTSD

Sujet: Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimers disease.

UniProt: P07339

Pathways: Peptide Hormone Metabolism