Cathepsin D anticorps

N° du produit ABIN7880203

Cet anticorps anti-Cathepsin D Monoclonal Souris (Clone CTSD-4497) (ABIN7880203) détecte spécifiquement Cathepsin D dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Cathepsin D anticorps (ABIN7880203)

Antigène: Cathepsin D (CTSD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CTSD-4497

Détail du produit anti-Cathepsin D anticorps

Fonction: CTSD Antibody / Cathepsin D

Purification: Protein A/G affinity

Immunogène: Purified His-tagged CTSD protein was used as the immunogen for the CTSD antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CTSD antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CTSD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: CTSD

Sujet: Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimers disease.

UniProt: P07339

Pathways: Peptide Hormone Metabolism