Recombinant CDC20 anticorps

N° du produit ABIN7880378

Cet anticorps Lapin Monoclonal détecte spécifiquement CDC20 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CDC20 anticorps (ABIN7880378)

Antigène: CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CDC20 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CDC20-7026R

Détail du produit anti-CDC20 anticorps

Fonction: Recombinant Cdc20 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant human Cdc20 protein was used as the immunogen for the recombinant Cdc20 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Cdc20 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Cdc20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CDC20

Antigène: CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))

Autre désignation: Cdc20

Sujet: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. [UniProt]

UniProt: Q12834