Claudin 1 anticorps

N° du produit ABIN7880442

L’anticorps anti-Claudin 1 Polyclonal Lapin est utilisé pour la détection de Claudin 1 dans des échantillons de Humain. Il a été validé pour IF et IHC (p).

Aperçu rapide pour Claudin 1 anticorps (ABIN7880442)

Antigène: Claudin 1 (CLDN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 1 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Claudin 1 anticorps

Fonction: Claudin 1 Antibody / CLDN1

Séquence: ATAWYGNRIV QEFYD

Purification: Affinity purified

Immunogène: Amino acids ATAWYGNRIVQEFYD from the human protein were used as the immunogen for the Claudin 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Claudin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Claudin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Claudin 1

Antigène: Claudin 1 (CLDN1)

Autre désignation: Claudin 1

Sujet: Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C