Claudin 7 anticorps

N° du produit ABIN7880451

L’anticorps anti-Claudin 7 Polyclonal Lapin est utilisé pour la détection de Claudin 7 dans des échantillons de Souris. Il a été validé pour WB.

Aperçu rapide pour Claudin 7 anticorps (ABIN7880451)

Antigène: Claudin 7 (CLDN7)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Claudin 7 anticorps

Fonction: Cldn7 Antibody / Claudin 7

Séquence: SESKAAYRAP RSYPKSNSSK EYV

Purification: Affinity purified

Immunogène: Amino acids SESKAAYRAPRSYPKSNSSKEYV from the mouse protein were used as the immunogen for the Cldn7 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cldn7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Cldn7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Cldn7

Sujet: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

UniProt: Q9Z261

Pathways: Hepatitis C