Dystrophin anticorps
Aperçu rapide pour Dystrophin anticorps (ABIN7880663)
Antigène
Voir toutes Dystrophin (DMD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Dystrophin Antibody / DMD
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Purification
- Affinity purified
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Immunogène
- A synthetic peptide specific to human Dystrophin / DMD was used as the immunogen for the Dystrophin antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Dystrophin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store the Dystrophin antibody at -20oC.
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- Dystrophin (DMD)
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Autre désignation
- Dystrophin
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Sujet
- The DMD gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [RefSeq]
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UniProt
- P11532
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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