Recombinant EPX anticorps
Aperçu rapide pour Recombinant EPX anticorps (ABIN7880695)
Antigène
Voir toutes EPX AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Eosinophil Peroxidase Antibody
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Purification
- Protein G affinity chromatography
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Immunogène
- Human eosinophils from a patient with hypereosinophilic syndrome were used as the immunogen for the recombinant Eosinophil Peroxidase antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the recombinant Eosinophil Peroxidase antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant Eosinophil Peroxidase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- EPX (Eosinophil Peroxidase (EPX))
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Autre désignation
- Eosinophil Peroxidase
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Sujet
- Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
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UniProt
- P11678
Antigène
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