ERCC1 anticorps

N° du produit ABIN7880754

L’anticorps anti-ERCC1 Monoclonal Lapin est utilisé pour la détection de ERCC1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ERCC1 anticorps (ABIN7880754)

Antigène: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ERCC1 est non-conjugé

Application: Western Blotting (WB)

Clone: AOFA-5

Détail du produit anti-ERCC1 anticorps

Fonction: ERCC1 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human ERCC1 was used as the immunogen for the ERCC1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ERCC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the ERCC1 antibody at -20oC.

Détails sur ERCC1

Antigène: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Autre désignation: ERCC1

Sujet: The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. [RefSeq]

UniProt: P07992

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response