Glutathione Peroxidase 1 anticorps

N° du produit ABIN7880892

L’anticorps anti-Glutathione Peroxidase 1 Monoclonal Lapin est utilisé pour la détection de Glutathione Peroxidase 1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Glutathione Peroxidase 1 anticorps (ABIN7880892)

Antigène: Glutathione Peroxidase 1 (GPX1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Glutathione Peroxidase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IHO-7

Détail du produit anti-Glutathione Peroxidase 1 anticorps

Fonction: GPX1 Antibody / Glutathione Peroxidase 1

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Glutathione Peroxidase 1 / GPX1 was used as the immunogen for the GPX1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GPX1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the GPX1 antibody at -20oC.

Détails sur Glutathione Peroxidase 1

Antigène: Glutathione Peroxidase 1 (GPX1)

Autre désignation: GPX1

Sujet: The protein encoded by the GPX1 gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. [RefSeq]

UniProt: P07203

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome