Recombinant HNRNPM anticorps

N° du produit ABIN7881033

L’anticorps anti-HNRNPM Monoclonal Lapin est utilisé pour la détection de HNRNPM dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, IF, ICC et FACS.

Aperçu rapide pour Recombinant HNRNPM anticorps (ABIN7881033)

Antigène: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HNRNPM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 29H77

Détail du produit anti-HNRNPM anticorps

Fonction: HNRNPM Antibody / heterogeneous nuclear ribonucleoprotein M

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human HNRNPM was used as the immunogen for the HNRNPM antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HNRNPM antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the HNRNPM antibody at -20oC.

Détails sur HNRNPM

Antigène: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Autre désignation: HNRNPM

Sujet: HNRNPM antibody recognizes heterogeneous nuclear ribonucleoprotein M, an RNA-binding protein involved in pre-mRNA processing and splicing regulation. HNRNPM is part of the hnRNP family, which associates with nascent transcripts to influence alternative splicing, stability, transport, and translation. This protein is widely expressed and contributes to the regulation of diverse gene expression programs in normal development and stress adaptation.

Research using HNRNPM antibody has linked the protein to cancer progression and metastasis. By regulating alternative splicing of genes related to epithelial-to-mesenchymal transition (EMT), HNRNPM promotes tumor invasiveness and metastatic potential. Elevated expression of HNRNPM has been associated with poor prognosis in breast, colorectal, and liver cancers. Its role in RNA processing makes it a critical factor in understanding how splicing dysregulation contributes to oncogenesis.

Beyond cancer, HNRNPM has been implicated in immune function and neurobiology. Studies suggest roles in regulating splicing of immune-related transcripts and neuronal genes, connecting HNRNPM to autoimmune conditions and neurological disorders. Its widespread impact on RNA metabolism positions HNRNPM as an important regulator of cellular identity and function.

Antibodies against HNRNPM are validated for western blot, immunoprecipitation, immunohistochemistry, and immunofluorescence. Researchers use these reagents to analyze HNRNPM expression, splicing complex assembly, and transcript-specific binding. Clone-based antibodies offer the specificity needed to study this protein within large multi-protein RNA processing complexes.

NSJ Bioreagents offers this HNRNPM antibody for investigations into RNA splicing, cancer biology, and immune regulation.

UniProt: P52272