IMPDH2 anticorps
Aperçu rapide pour IMPDH2 anticorps (ABIN7881162)
Antigène
Voir toutes IMPDH2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Inosine-5'-monophosphate dehydrogenase 2 Antibody / IMPDH2
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Séquence
- VVLSPKDRVR DVFEAKARH
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Purification
- Antigen affinity purified
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Immunogène
- Amino acids VVLSPKDRVRDVFEAKARH were used as the immunogen for the Inosine-5'-monophosphate dehydrogenase 2 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Inosine-5'-monophosphate dehydrogenase 2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Inosine-5'-monophosphate dehydrogenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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Autre désignation
- Inosine-5'-monophosphate dehydrogenase 2
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Sujet
- Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene. This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
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UniProt
- P12268
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Pathways
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
Antigène
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