IFNA1 anticorps

N° du produit ABIN7881253

Cet anticorps anti-IFNA1 Monoclonal Souris (Clone 2-48) (ABIN7881253) détecte spécifiquement IFNA1 dans WB, FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IFNA1 anticorps (ABIN7881253)

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 2-48

Détail du produit anti-IFNA1 anticorps

Fonction: IFNA1 Antibody / Interferon alpha 1

Purification: Protein G affinity chromatography

Immunogène: Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the IFNA1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the IFNA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur IFNA1

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Autre désignation: IFNA1

Sujet: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

UniProt: P01562

Pathways: Signalistation JAK/STAT, Hepatitis C