Keratin 7/17 anticorps

N° du produit ABIN7881418

L’anticorps anti-Keratin 7/17 Monoclonal Souris est utilisé pour la détection de Keratin 7/17 dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et IF.

Aperçu rapide pour Keratin 7/17 anticorps (ABIN7881418)

Antigène: Keratin 7/17 (KRT7/17)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 7/17 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Classe de qualité: Carrier-free

Clone: C-46

Détail du produit anti-Keratin 7/17 anticorps

Fonction: Cytokeratin 7/17 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A cytoskeletal preparation from human HeLa cells was used as the immunogen for this Cytokeratin 7/17 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cytokeratin 7/17 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cytokeratin 7/17 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Keratin 7/17

Antigène: Keratin 7/17 (KRT7/17)

Autre désignation: Cytokeratin 7/17

Sujet: It recognizes intermediate filament proteins (IFP's) of 55 kDa and 46 kDa, which are identified as Cytokeratin 7 and Cytokeratin 17 respectively. On formalin-fixed, paraffin embedded sections, C-46 reacts with Keratin 7 only. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Cytokeratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. Cytokeratin 17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. Cytokeratin 17 antibody marks basal cell differentiation.

UniProt: P08729