MMP2 anticorps

N° du produit ABIN7881559

L’anticorps anti-MMP2 Monoclonal Souris est utilisé pour la détection de MMP2 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour MMP2 anticorps (ABIN7881559)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MMP2-4586

Détail du produit anti-MMP2 anticorps

Fonction: Matrix metalloproteinase 2 Antibody / MMP2

Purification: Protein A/G affinity

Immunogène: Recombinant human protein was used as the immunogen for the Matrix metalloproteinase 2 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Matrix metalloproteinase 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Matrix metalloproteinase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: Matrix metalloproteinase 2

Sujet: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

UniProt: P08253

Pathways: Activation of Innate immune Response