MMP2 anticorps

N° du produit ABIN7881560

Cet anticorps anti-MMP2 Monoclonal Lapin (Clone BBA-13) (ABIN7881560) détecte spécifiquement MMP2 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour MMP2 anticorps (ABIN7881560)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: BBA-13

Détail du produit anti-MMP2 anticorps

Fonction: MMP2 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human MMP2 was used as the immunogen for the MMP2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MMP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the MMP2 antibody at -20oC.

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2

Sujet: The MMP2 gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. [RefSeq]

UniProt: P08253

Pathways: Activation of Innate immune Response