MAP4K3 anticorps

N° du produit ABIN7881655

L’anticorps anti-MAP4K3 Monoclonal Souris est utilisé pour la détection de MAP4K3 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour MAP4K3 anticorps (ABIN7881655)

Antigène: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAP4K3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 219CT8-3-1

Détail du produit anti-MAP4K3 anticorps

Fonction: MAP4K3 Antibody / MEKKK3 / GLK

Purification: Purified

Immunogène: Recombinant human protein was used as the immunogen for the MAP4K3 antibody.

Isotype: IgM, kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the MAP4K3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the MAP4K3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MAP4K3

Antigène: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Autre désignation: MAP4K3

Sujet: This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).

UniProt: Q8IVH8

Pathways: Signalisation MAPK