Moesin anticorps

N° du produit ABIN7881659

Cet anticorps anti-Moesin Monoclonal Souris (Clone SPM562) (ABIN7881659) détecte spécifiquement Moesin dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Moesin anticorps (ABIN7881659)

Antigène: Moesin (MSN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Moesin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM562

Détail du produit anti-Moesin anticorps

Fonction: Moesin Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for this Moesin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The optimal dilution of the Moesin antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Moesin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Moesin

Antigène: Moesin (MSN)

Autre désignation: Moesin

Sujet: Recognizes 78 kDa moesin protein. Moesin, a member of the Talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

UniProt: P26038

Pathways: Asymmetric Protein Localization