MUC5AC anticorps (Biotin)

N° du produit ABIN7881679

L’anticorps anti-MUC5AC Monoclonal Souris est utilisé pour la détection de MUC5AC dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC (p).

Aperçu rapide pour MUC5AC anticorps (Biotin) (ABIN7881679)

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC5AC est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 45M1

Détail du produit anti-MUC5AC anticorps (Biotin)

Fonction: MUC5AC Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: An M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for the biotinylated MUC5AC antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the biotinylated MUC5AC antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the biotinylated MUC5AC antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).

Détails sur MUC5AC

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Autre désignation: MUC5AC

Sujet: This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

UniProt: P98088