MUC6 anticorps

N° du produit ABIN7881683

Cet anticorps anti-MUC6 Monoclonal Souris (Clone SPM598) (ABIN7881683) détecte spécifiquement MUC6 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MUC6 anticorps (ABIN7881683)

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC6 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM598

Détail du produit anti-MUC6 anticorps

Fonction: Anti-MUC6 Antibody (Gastric Mucin)

Purification: Protein G affinity chromatography

Immunogène: A synthetic peptide of the gastric Mucin 6 tandem repeat sequence was used as the immunogen for the anti-MUC6 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the anti-MUC6 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the anti-MUC6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MUC6

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Autre désignation: MUC6

Sujet: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

UniProt: Q6W4X9