MYOD1 anticorps

N° du produit ABIN7881721

L’anticorps anti-MYOD1 Monoclonal Souris est utilisé pour la détection de MYOD1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour MYOD1 anticorps (ABIN7881721)

Antigène: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYOD1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MYOD1-7149

Détail du produit anti-MYOD1 anticorps

Fonction: MyoD1 Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant mouse MyoD1 protein was used as the immunogen for the MyoD1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the MyoD1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MyoD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MYOD1

Antigène: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Autre désignation: MyoD1

Sujet: Recognizes a phosphor-protein of 45 kDa, identified as MyoD1. The epitope of this mAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.

UniProt: P15172

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development