Nucleolin anticorps (CF®488A)

N° du produit ABIN7881850

L’anticorps anti-Nucleolin Monoclonal Souris est utilisé pour la détection de Nucleolin dans des échantillons de Humain. Il a été validé pour IF et FACS.

Aperçu rapide pour Nucleolin anticorps (CF®488A) (ABIN7881850)

Antigène: Nucleolin (NCL)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Nucleolin est conjugé à/à la CF®488A

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: NCL-902

Détail du produit anti-Nucleolin anticorps (CF®488A)

Fonction: Nucleolin Antibody

Purification: Protein G affinity chromatography

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Nucleolin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the Nucleolin antibody at 2-8oC, protected from light.

Détails sur Nucleolin

Antigène: Nucleolin (NCL)

Autre désignation: Nucleolin

Sujet: Recognizes a protein of ~76 kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.

UniProt: P19338

Pathways: Ribonucleoprotein Complex Subunit Organization