Patched 2 anticorps

N° du produit ABIN7881908

Cet anticorps anti-Patched 2 Polyclonal Lapin (ABIN7881908) détecte spécifiquement Patched 2 dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Patched 2 anticorps (ABIN7881908)

Antigène: Patched 2 (PTCH2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Patched 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Patched 2 anticorps

Fonction: Patched 2 Antibody / PTCH2

Séquence: FDYAHSQRAL FDLHQR

Purification: Affinity purified

Immunogène: Amino acids FDYAHSQRALFDLHQR from the human protein were used as the immunogen for the Patched 2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Patched 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Patched 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Patched 2

Antigène: Patched 2 (PTCH2)

Autre désignation: Patched 2

Sujet: PTCH2 (patched 2), also known as PTC2, encodes a 1.203-amino acid putative transmembrane protein that is highly homologous to the PTCH product. The Patched-hedgehog signaling pathway is involved in establishing segment polarity and the anterior-posterior orientation of a number of developing appendages. The pathway is conserved from fly to vertebrates and has been implicated in a number of human neoplasms and developmental syndromes. Mutations in the human Patched gene are the basis of the nevoid basal cell carcinoma syndrome. With age, homozygous mutant male mice developed skin lesions consisting of alopecia and epidermal hyperplasia, suggesting a role for Ptch2 in adult epidermal homeostasis via Shh signaling.

UniProt: Q9Y6C5

Pathways: Signalisation Hedgehog