Recombinant POLG anticorps

N° du produit ABIN7881999

Cet anticorps Lapin Monoclonal détecte spécifiquement POLG dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant POLG anticorps (ABIN7881999)

Antigène: POLG (Polymerase (DNA Directed), gamma (POLG))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp POLG est non-conjugé

Application: Western Blotting (WB)

Clone: 24P93

Détail du produit anti-POLG anticorps

Fonction: POLG Antibody / DNA polymerase subunit gamma 1

Purification: Affinity chromatography

Immunogène: A peptide sequence specific to DNA polymerase subunit gamma 1 was used as the immunogen for the POLG antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the POLG antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the POLG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur POLG

Antigène: POLG (Polymerase (DNA Directed), gamma (POLG))

Autre désignation: POLG

Sujet: DNA polymerase subunit gamma 1 (POLG) is the catalytic subunit of the mitochondrial DNA polymerase complex, responsible for replication and repair of mitochondrial DNA. POLG ensures accurate DNA synthesis within mitochondria, which is essential for proper oxidative phosphorylation and cellular energy production.

Mutations in POLG are associated with a range of mitochondrial disorders, including progressive external ophthalmoplegia, Alpers-Huttenlocher syndrome, and ataxia-neuropathy syndromes. Studying POLG function helps researchers understand mitochondrial genome maintenance and the molecular basis of mitochondrial diseases.

Using a high-quality POLG antibody allows for sensitive detection of the protein in assays such as western blot, immunohistochemistry, and immunofluorescence. A POLG antibody from NSJ Bioreagents offers consistent performance, supporting studies in mitochondrial biology, genetic disorders, and DNA repair mechanisms. Choosing the right POLG antibody is critical for producing reliable and reproducible research results.

UniProt: P54098