POGLUT1 anticorps

N° du produit ABIN7882078

L’anticorps anti-POGLUT1 Polyclonal Lapin est utilisé pour la détection de POGLUT1 dans des échantillons de Humain et Souris. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour POGLUT1 anticorps (ABIN7882078)

Antigène: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POGLUT1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-POGLUT1 anticorps

Fonction: POGLUT1 Antibody / CLP46 / Rumi

Séquence: KTDLSNVQEL LQFVKANDDV AQEIAER

Purification: Affinity purified

Immunogène: Amino acids KTDLSNVQELLQFVKANDDVAQEIAER from the human protein were used as the immunogen for the POGLUT1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the POGLUT1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the POGLUT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur POGLUT1

Antigène: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Autre désignation: POGLUT1

Sujet: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.

UniProt: Q8NBL1

Pathways: Signalisation Notch