PNP anticorps

N° du produit ABIN7882108

L’anticorps anti-PNP Monoclonal Souris est utilisé pour la détection de PNP dans des échantillons de Humain et Rat. Il a été validé pour WB.

Aperçu rapide pour PNP anticorps (ABIN7882108)

Antigène: PNP (Purine Nucleoside Phosphorylase (PNP))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PNP est non-conjugé

Application: Western Blotting (WB)

Clone: 2H10

Détail du produit anti-PNP anticorps

Fonction: Purine nucleoside phosphorylase Antibody / PNP / Inosine phosphorylase

Séquence: AMSDAYDRTM RQRALSTWKQ MGEQRELQE

Purification: Antigen affinity purified

Immunogène: Amino acids AMSDAYDRTMRQRALSTWKQMGEQRELQE were used as the immunogen for the Purine nucleoside phosphorylase antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Purine nucleoside phosphorylase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PNP

Antigène: PNP (Purine Nucleoside Phosphorylase (PNP))

Autre désignation: Purine nucleoside phosphorylase

Sujet: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

UniProt: P00491

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus