PNP anticorps

N° du produit ABIN7882109

Cet anticorps anti-PNP Monoclonal Souris (Clone 7G5) (ABIN7882109) détecte spécifiquement PNP dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PNP anticorps (ABIN7882109)

Antigène: PNP (Purine Nucleoside Phosphorylase (PNP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PNP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7G5

Détail du produit anti-PNP anticorps

Fonction: PNP Antibody / Inosine phosphorylase / Purine nucleoside phosphorylase

Séquence: AMSDAYDRTM RQRALSTWKQ MGEQRELQE

Purification: Antigen affinity purified

Immunogène: Amino acids AMSDAYDRTMRQRALSTWKQMGEQRELQE were used as the immunogen for the PNP antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the PNP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PNP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PNP

Antigène: PNP (Purine Nucleoside Phosphorylase (PNP))

Autre désignation: PNP

Sujet: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

UniProt: P00491

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus