PDHA1 anticorps

N° du produit ABIN7882116

Cet anticorps Lapin Monoclonal détecte spécifiquement PDHA1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PDHA1 anticorps (ABIN7882116)

Antigène: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PDHA1 est non-conjugé

Application: Western Blotting (WB)

Clone: AODI-16

Détail du produit anti-PDHA1 anticorps

Fonction: PDHA1 Antibody / Pyruvate Dehydrogenase E1 Alpha

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Pdh E1 Alpha / PDHA1 was used as the immunogen for the PDHA1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PDHA1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the PDHA1 antibody at -20oC.

Détails sur PDHA1

Antigène: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Autre désignation: PDHA1

Sujet: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. [RefSeq]

UniProt: P08559

Pathways: L'effet Warburg