SKIP anticorps

N° du produit ABIN7882277

Cet anticorps anti-SKIP Monoclonal Souris (Clone PCRP-SNW1-2A1) (ABIN7882277) détecte spécifiquement SKIP dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SKIP anticorps (ABIN7882277)

Antigène: SKIP

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-SNW1-2A1

Détail du produit

Fonction: SKIP Antibody / SNW1 / NCoA-62 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant fragment of human protein was used as the immunogen for the SKIP antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the SKIP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the SKIP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: SKIP

Sujet: Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

UniProt: Q13573