SKIP anticorps

N° du produit ABIN7882278

Cet anticorps Souris Monoclonal détecte spécifiquement SKIP dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SKIP anticorps (ABIN7882278)

Antigène: SKIP

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS)

Clone: PCRP-SNW1-2A1

Détail du produit

Fonction: SKIP Antibody / SNW1 / NCoA-62

Purification: Protein A/G affinity

Immunogène: A recombinant fragment of human protein was used as the immunogen for the SKIP antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the SKIP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SKIP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: SKIP

Sujet: Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

UniProt: Q13573