Spectrin beta Chain, Erythrocyte (SPTB) anticorps

N° du produit ABIN7882347

Cet anticorps Souris Monoclonal détecte spécifiquement Spectrin beta Chain, Erythrocyte dans WB, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Spectrin beta Chain, Erythrocyte (SPTB) anticorps (ABIN7882347)

Antigène: Spectrin beta Chain, Erythrocyte (SPTB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: RG-26

Détail du produit

Fonction: SPTB Antibody / Spectrin beta (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Red cell membranes were used as the immunogen for this Spectrin beta antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the SPTB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the SPTB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détail du antigène

Antigène: Spectrin beta Chain, Erythrocyte (SPTB)

Autre désignation: SPTB

Sujet: Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.

UniProt: P11277

Pathways: Regulation of Actin Filament Polymerization