Stathmin 1 anticorps

N° du produit ABIN7882368

Cet anticorps Souris Monoclonal détecte spécifiquement Stathmin 1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Stathmin 1 anticorps (ABIN7882368)

Antigène: Stathmin 1 (STMN1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Stathmin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: STMN1-8437

Détail du produit anti-Stathmin 1 anticorps

Fonction: Stathmin 1 Antibody / STMN1

Purification: Protein A/G affinity

Immunogène: A recombinant fragment of human STMN1 protein was used as the immunogen for the Stathmin 1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Stathmin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Stathmin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Stathmin 1

Antigène: Stathmin 1 (STMN1)

Autre désignation: Stathmin 1

Sujet: Stathmin 1 (Oncoprotein 18, STM1, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of the protein are observed, and it is expressed as two different isoforms. Stathmin 1 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. It is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

UniProt: P16949

Pathways: Signalisation MAPK, Dynamique des Microtubules